Welcome to ProMOL. In recent years, structural genomics initiatives have generated a large number of protein structures. However, determining the function of these proteins through traditional experimental procedures can be a slow process. This disparity has been the motivation behind the creation of computational tools to predict function from structural homology. ProMOL is a plugin for the molecular visualization program, PyMOL, which uses catalytic site homology to predict the function of proteins with no known function.ProMOL's Motif Finder ![]() Alignment of the query protein 1rbn (red) with motif protein 5rsa (white).
ProMOL includes the ability to:
The ProMol project is sponsored by grants NSF-DUE 0402408, NIGMS 1R15GM078077, NIGMS 2R15GM078077-02, NIGMS 3R15GM078077-02S1, and NSF 1503811 and in part by Rochester Institute of Technology and Dowling College.
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